Our Research

We develop new approaches to nanoparticle surface engineering that move beyond conventional PEGylation, seeking materials that retain effective shielding while enabling repeat dosing and productive interactions with biological systems.

We design delivery materials that do more than carry nucleic acids. By considering how carrier chemistry interacts with innate and adaptive immunity, we aim to engage, direct or temper immune responses alongside the cargo.

We investigate how ligand design, surface architecture and formulation strategy can control where nucleic acid medicines go, how they enter cells and where their cargo becomes available.

We use analytical methods to reveal the physicochemical fingerprints of complex delivery systems and build clearer links between their composition, structure, stability and biological performance.